This book, "Quantum Laser-Tissue Interactions: A New Era in Precision Medical Therapy," explores the groundbreaking application of quantum physics principles—including quantum optics, mechanics, and metrology—to revolutionize medical laser technology. It details how advanced quantum-enabled strategies, such as using tightly controlled multi-photon states and non-classical light, facilitate highly sophisticated laser properties. The transformative approach outlined significantly intensifies the interaction with biological tissues, leading to enhanced precision in target selection while minimizing collateral damage to surrounding cells, thus vastly broadening the scope of treatable tissues compared to conventional lasers. The text rigorously examines the Foundations of Quantum-Enhanced Laser-Tissue Interactions, delving into the underlying quantum-driven mechanisms such as coherence, entanglement, and quantum tunneling that govern molecular and cellular responses. It covers advanced Laser Modalities (including pulsed and ultrafast strategies) and the necessary Technological Enablers and Instrumentation, such as quantum-enhanced light sources and detectors. Finally, the volume addresses critical topics like Safety, Ethics, and Regulatory Considerations and the use of Computational and Simulation Frameworks—including machine learning—to optimize treatment protocols, paving the way for revolutionary advancements in medical science and therapeutic practices.